Click Here to Subscribe: http://Bit.ly/ThomasVid Get Grass-Finished Meat Delivered to Your Doorstep with Butcher Box: https://butcherbox.pxf.io/c/1434763/1577973/16419 My Website: http://ThomasDeLauer.com Best Meats to Eat | Low Carb High Fat Diet | Protein Fatty Acids Comparison (Meat Analysis) Beef (per 100g)- Calories: ~255 Fat: 20g Saturated: 7.7g Monounsaturated: 8.8g Polyunsaturated: 0.5g Omega 3: 48mg Omega 6: 435mg 6 to 3 ratio: 9:1 Notable Fats: stearic acid, oleic acid, and palmitic acid.
Chicken (per 100g)- Calories: ~140 Fat: 8.1g Saturated: 2.3g Monounsaturated: 3.6g Polyunsaturated: 1.5g Omega 3: 96mg Omega 6: 1327mg 6 to 3 ratio: 13.8:1 Notable Fats: Linoleic and low content of stearic.
Bison- Calories: ~145 Fat: 7.2 g Saturated: 2.9 g Monounsaturated: 2.8 g Polyunsaturated: 0.3 g Omega 3: 38 mg Omega 6: 261 mg 6 to 3 ratio: 6.9 : 1 Notable Fats: Stearic and linolenic.
Pork- Calories: ~260 Fat: 21 g Saturated: 7.9 g Monounsaturated: 9.4 g Polyunsaturated: 1.9 g Omega 3: 70 mg Omega 6: 1670 mg 6 to 3 ratio: 23.8 : 1 Notable Fats: Oleic and palmitic acids.
Monounsaturated Fats: Monounsaturated fat molecules are not saturated with hydrogen atoms - each fat molecule has only the space for one hydrogen atom.
Oleic Acid - Monounsaturated Fat Oleic acid benefits the myelin sheath as it’s one of the most common fats in myelin.
Oleic acid regulates the activity of adrenoceptor signaling pathways which direct the adrenergic receptors (α- and β-adrenoceptors) that help regulate blood pressure.
Oleic acid can also increase fat oxidation as it increases the expression of genes involved in fat burning.
Specifically, oleic acid stimulates the cAMP/protein kinase a pathway and activates the SIRT1-PGC1α transcriptional complex to modulate rates of fatty acid oxidation.
Polyunsaturated Fat: In polyunsaturated fats, there are a number of spaces around each polyunsaturated fat molecule - they are not saturated with hydrogen atoms.
Alpha Linolenic Acid – Polyunsaturated: ALA is an omega 3, but it’s a precursor to EPA and DHA - the conversion rate in our bodies is extremely low – often less than 1% of ALA is converted to EPA and DHA.
Omega 3 vs 6 Overview - Polyunsaturated Fat: Eicosapentaenoic acid (EPA) - main function is to produce signaling molecules called eicosanoids, which help reduce inflammation.
Docosahexaenoic acid (DHA) - important for healthy brain development and function.
Most common omega 6 is linoleic acid (LA) - LA is either burned as energy or converted into longer omega-6 fats such as arachidonic acid (ARA.) Saturated Fat: Stearic Acid - Saturated Fat- Stearic acid ingestion rapidly and robustly causes mitochondrial fusion in people.
When stearic acid levels are low, the Transferrin Receptor TfR1 activates JNK signaling, leading to ubiquitination and inhibition of Mitofusin 2 and hence mitochondrial fragmentation and reduced oxygen consumption.
In the presence of stearic acid, the fatty acid molecule is covalently attached to TfR1 via a thioester bond in a post-translational modification called stearoylation, analogous to protein palmitoylation by palmitic acid.
This leads to reduced JNK activation by TfR1, to mitochondrial fusion, and to elevated oxygen consumption.
So stearic acid stearoylates TFR1, thereby inhibiting its activation of JNK signalling - this leads to reduced ubiquitination of mitofusin via HUWE1, thereby promoting mitochondrial fusion and function.
Palmitic Acid - Saturated Fat: Palmitic acid has historically been depicted as 'unhealthy, but a review published in Frontiers in Physiology looked at the role it plays in human health.
Palmitic acid has a critical role in cellular membrane functionality by affecting their 'flexibility' and permeability and it forms reversible links to cell membrane proteins.
Conjugated Linoleic Acid - Trans Fat: Conjugated linoleic acids are polyunsaturated fatty acids containing both cis- and trans- bonds as well as double bonds.
The CLA cis-9, trans-11 is mostly found in foods, whereas trans-10,cis-12 is found in supplements.
Resources: 1) https://nutritiondata.self.com/facts/poultry-products/10049/2 2) https://nutritiondata.self.com/facts/beef-products/6203/2 3) https://nutritiondata.self.com/facts/pork-products/2280/2 4) https://nutritiondata.self.com/facts/lamb-veal-and-game-products/10628/2 5) https://www.ncbi.nlm.nih.gov/pubmed/10347702 6)https://www.sciencedirect.com/science/article/pii/0889157589900793 7)https://www.frontiersin.org/articles/10.3389/fphys.2017.00902/full 8)https://link.springer.com/article/10.1007/s11746-000-0156-8 9)https://www.ahajournals.org/doi/full/10.1161/01.ATV.17.9.1657 10)https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1853362/ 11)https://www.ncbi.nlm.nih.gov/pubmed/30087348 12) https://www.nature.com/articles/s41467-018-05614-6 13) https://www.ncbi.nlm.nih.gov/pubmed/26214738?dopt=Abstract
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